1、病原共感染模型，微生物共培养，及微生物相互作用机制的研究。

2、病原微生物与宿主的相互作用和免疫机制的研究。

3、微生物组学研究。建立了多条件微生物培养平台，可对包括严格厌氧菌在内的多种微生物进行培养研究。

科研项目（课题）

1. 国家自然科学基金委员会，青年科学基金项目，32001080：蓝藻-曲霉共培养合成聚酮化合物研究及藻菌互作机制的解析，2021-01至2023-12，主持

发表论文

1. Tingting Li, Dongxia Liu, Yadi Yang, Jiali Guo, Yujie Feng, Xinmo Zhang, Shilong Cheng, Jie Feng. (2020) Phylogenetic supertree reveals detailed evolution of SARS?CoV?2, Scientific Reports, 10:22366. https://doi.org/10.1038/s41598-020-79484-8

2. Tingting Li, Liqun Jiang, Yifeng Hu, Jackson T Paul, Cristal Zuniga, Karsten Zengler, Michael J Betenbaugh. (2020) Creating a synthetic lichen: Mutualistic co-culture of fungi and extracellular polysaccharide-secreting cyanobacterium Nostoc PCC 7413, Algal research, 45: 101755.

3. Cristal Zu?iga, Tingting Li, Michael Guarnieri, Jackson P Jenkins, Chien-Ting Li, Kerem Bingol, Young-Mo Kim, Michael J Betenbaugh, and Karsten Zengler. (2020) Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth. Nature Communications 11(1):1-13.

4. Jiang, Liqun, Tingting Li, Jackson Jenkins, Yifeng Hu, Christopher L Brueck, Haiyan Pei, and Michael J Betenbaugh. (2020) Evidence for a mutualistic relationship between the cyanobacteria Nostoc and fungi Aspergilli in different environments. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-020-10663-3

5. Xiaoyan Zheng, Xiao Ma, Tingting Li, Wanliang Shi, and Ying Zhang. (2020) Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of Bartonella henselae in vitro, BMC microbiology, 20: 1-9.

6. Cristal Zu?iga, Chien-Ting Li, Geng Yu, Mahmoud M. Al-Bassam, Tingting Li, Liqun Jiang, Livia S. Zaramela1, Michael Guarnieri, Michael J. Betenbaugh, Karsten Zengler. (2019) Environmental stimuli drive a transition from cooperation to competition in synthetic phototrophic communities. Nature Microbiology, 1-8.

7. Tingting Li, Jie Feng, Shuzhen Xiao, Wanliang Shi, David Sullivan, Ying Zhang. (2019) Identification of FDA-Approved Drugs with Activity against Stationary Phase Bartonella henselae. Antibiotics, 8(2):50.

8. Jie Feng, Tingting Li, Rebecca Yee, Chunxiang Bai, Menghua Cai, Wanliang Shi, Monica Embers, Cory Brayton, Harumi Saeki, Kathleen Gabrielson, Ying Zhang. (2019) Stationary phase persister/biofilm microcolony of Borrelia burgdorferi causes more severe disease in a mouse model of Lyme arthritis: implications for understanding persistence, Post-treatment Lyme Disease Syndrome (PTLDS), and treatment failure. Discovery Medicine, 27(148): p. 125-138.

9. Tingting Li, Kirk Butler, Chien-Ting Li, Stephanie Hays, Pamela A. Silver, Michael J. Betenbaugh. (2017) Mimicking lichens: Incorporation of yeast strains together with sucrose-secreting cyanobacteria improves survival, growth, ROS removal, and lipid production in a stable mutualistic co-culture production platform. Biotechnology for Biofuels, DOI: 10.1186/s13068-017-0736-x.

10. Tingting Li, Helmut Kirchhoff, Mahmoud Gargouri, Jie Feng, Philip T. Pienkos, David Gang, Shulin Chen. (2016) Assessment of photosynthesis regulation in mixotrophically cultured microalga Chlorella sorokiniana. Algal Research, 19:30-38.

11. Chao Miao, Oscar Marin-Flores, Stephen D. Davidson, Tingting Li, Tao Dong, Difeng Gao, Yong Wang, Manuel Garcia-Péreza, Shulin Chen. (2016) Hydrothermal catalytic deoxygenation of palmitic acid over nickel catalyst. Fuel, 166: 302-308.

12. Tingting Li, Mahmoud Gargouri, Jie Feng, Jeong-Jin Park, Difeng Gao, Chao Miao, Tao Dong, David Gang, Shulin Chen. (2015) Regulatory mechanism of starch and lipid accumulation in microalga strain Chlorella sorokiniana. Bioresource Technology, 180: 250-257.

13. Xin Du, Moran Li, Wei Tang, Yaoxin Zhang, Li Zhang, Jian Wang, Tingting Li, Bing Tang, Xiao-Feng Tang. (2015) Secretion of Tat-dependent halolysin SptA capable of autocatalytic activation and its relation to haloarchaeal growth. Molecular Microbiology, 96: 548-565.

14. Tao Dong, Liang Yu, Difeng Gao, Xiaochen Yu, Chao Miao, Yubin Zheng, Jieni Lian, Tingting Li, Shulin Chen. (2015) Direct quantification of fatty acids in wet microalgal and yeast biomass via a rapid in situ fatty acid methyl ester derivatization approach. Applied Microbial Biotechnology, DOI 10.1007/s00253-015-6909-2.

15. Tingting Li, Yubin Zheng, Liang Yu, Shulin Chen. (2014) Mixotrophic cultivation of Chlorella sorokiniana for enhanced biomass and lipid production. Biomass and Bioenergy, 66:204-213.

16. Tingting Li, Jijiao Zeng, Deepak Singh, Shulin Chen. (2014) New insights into the role of termite Coptotermes formosanus inhabiting Streptomyces in degradation of lignin. Journal of Bioremediation & Biodegradation, 5:220. doi:10.4172/2155-6199.1000220

17. Yubin Zheng, Xiaochen Yu, Tingting Li, Xiaochao Xiong, Shulin Chen. (2014) Induction of D-xylose uptake and expression of NAD(P)H-linked xylose reductase and NADP+-linked xylitol dehydrogenase in the oleaginous microalga Chlorella sorokiniana. Biotechnology for Biofuels, 7: 125.

18. Tingting Li, Yubin Zheng, Liang Yu, Shulin Chen. (2013) High productivity cultivation of a heat-resistant microalgae Chlorella sorokiniana for biofuel production. Bioresource Technology, 131:60-67.

19. Yubin Zheng, Tingting Li, Xiaochen Yu, Philip D. Bates, Tao Dong, Shulin Chen. (2013) High-density fed-batch culture of a thermotolerant microalga Chlorella sorokiniana for biofuel production. Applied Energy, 108: 281-287

20. Zhisheng Xu, Xin Du, Tingting Li, Fei Gan, Bing Tang, Xiao-Feng Tang. (2011) Functional Insight into the C-Terminal Extension of Halolysin SptA from Haloarchaeon Natrinema sp. J7. Plos One, 6:e23562