职 务:
职 称:副教授、硕士生导师
电子邮箱:zhangff@lzu.edu.cn
科研方向:COPD的发病机制与干预治疗;肿瘤发病机制与免疫治疗
张芳芳,副教授,硕士生导师,兰州大学基础医学院病理学研究所。 2007年毕业于中国科学院大学;2008年至2011年于美国路易斯安娜州立大学健康医学中心从事博士后研究工作,研究方向为肿瘤发病机理;2012年至2016年在美国纽约石溪大学从事肺纤维化治疗干预博士后研究工作。2016年3月加入兰州大学基础医学院病理学研究所。欢迎有志于从事COPD和肿瘤学研究的同学加入本课题组。研究背景不限于医学专业。
Resume
Postdoc: Stony Brook University, Department of Pathology
Postdoc: Louisiana State University, Health Sciences Center, Department of Microbiology and Immunology
Ph. D.: Institute of Zoology, Chinese Academy of Sciences
科研方向
1. COPD的发病机制与干预治疗
2. 肿瘤发病机制与免疫治疗
Research Interest
1. Pathogenesis and therapy of COPD.
2. Pathogenesis and immune therapy of cancer.
发表论文 Publications
1. F Zhang, Z Jiang, A Xu, Y Zeng, C Li. Recent geological events and intrinsic behavior influence the population genetic structure of the chiru and Tibetan gazelle on the Tibet Plateau. PLos One, 2013. 04. 24, 8(4):e60712.
2. S Avasarala#, F Zhang#, G Liu, R Wang, SD London, and L London. Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Model of Viral-induced Acute Respiratory Distress Syndrome, PLos One, 2013. 2. 20, 8(2): e57258 (#Co-first Author)
3. F Zhang, Z Jiang, Y Zeng, T McCarthy. Developement of primers to characterize the mitochondrial control region of snow leopard (uncia uncia). Molecular Ecology Notes. 2007, 7(6): 1196-1198.
4. F Zhang, Z Jiang. Mitochondrial phylogeography and genetic diversity of Tibetan gazelle (Procapra picticaudata): Implicatons for conservation. Molecular Phylogenetics and Evolution. 2006, 41: 313-321.
5. G Liu, F Zhang, R Wang, SD London, L London. Salivary gland immunization via Wharton’s duct activates differential T-cell responses within the salivary gland immune system, The FASEB Journal, 2019.
6. G Liu, F Zhang, R Wang, L London, SD London. Protective MCMV immunity by vaccination of the salivary gland via Wharton’s duct: replication-deficient recombinant adenovirus expressing individual MCMV genes elicits protection similar to that of MCMV, The FASEB Journal, 2014. 01. 03, 28(4): 1698-1710.
7. G Liu, F Zhang, J Shi, G Tian, H Chen, K Yu, Q Men. A subunit vaccine candidate derived from a classic H5N1 avian influenza virus in China protects fowls and BALB/c mice from lethal challenge, Vaccine, 2013. 11. 04, 31 (46):5389-5404.
8. K J Queen, M Shi, F Zhang, U Cvek and R S Scott. Epstein-Barr virus Induced Epigenetic Alterations Following Transient Infection. International Journal of Cancer, 2013. 05.01, 132(9):2076-2086.
9. K Ikuta, M Ding, F Zhang, J W. Sixbey and R S. Scott. Epithelial cell retention of transcriptionally active, P3HR-1-Derived heterogeneous (het) EBV DNA with concurrent loss of parental virus. Journal of Virology. 2011, 85(15): 7634-7543.
10. Y Luo, H Zhou, L Liu, T Shen, W Chen, B Xu, X Han, F Zhang, RS Scott, JS Alexander, A Alam and S Huang. The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway. Oncogene. 2010,1-10.
11. 张芳芳,姜永萍,刘光亮,陈怀涛,乔传玲,陈化兰. 表达禽流感病毒H5HA、H7HA基因DNA疫苗的免疫原性研究.预防兽医学报.2006,28:1-5.
12. 张芳芳,刘光亮,姜永萍,陈化兰,陈怀涛.禽流感病毒H5HA,H7HA基因共表达核酸疫苗质粒的构建及其在体外的表达. 动物医学进展.2004,25:107-110
13. 张芳芳,陈化兰,陈怀涛.增强DNA疫苗免疫效果的研究进展.动物医学进展.2004,5:41-43.
14. 姜永萍,李呈军,张洪波,步志高,张芳芳,邓国华,于康震,陈化兰.含有鸡体偏嗜性密码子的H5亚型禽流感病毒HA基因的优化构建及其DNA疫苗体外瞬时表达研究.预防兽医学报.2005,27:441-444,449.