刘欣

职  务:

职  称:萃英博士后

电子邮箱:l_x@lzu.edu.cn

科研方向:基于多肽可控自组装的生物医用功能材料的研发

刘欣,理学博士,兰州大学基础医学博士后流动站萃英博士后。2024年毕业于南开大学化学学院高分子化学与物理专业,获理学博士学位。主要研究方向为基于多肽可控自组装的生物医用功能材料的研发,在Acc. Chem. Res.JACSAngew. Chem. Int. Ed.Adv. Mater.国际著名期刊上累计发表学术论文16篇。

  1. Liu X#, Hu B#, Yu Z*. Noncanonical Amino Acids Dictate Peptide Assembly in Living Cells. Accounts of Chemical Research, 2025, 58, 1081-1093.
  2. Liu X, Tian F, Zhang Z, Liu J, Wang S, Guo R-C, Hu B, Wang H, Zhu H, Liu A-A, Shi L, Yu Z*. In Vivo Self-Sorting of Peptides via In Situ Assembly Evolution. Journal of the American Chemical Society, 2024, 146, 10753-10766.
  3. Liu X#, Li M#, Liu J, Song Y, Hu B, Wu C, Liu A-A, Zhou H, Long J, Shi L, Yu Z*. In Situ Self-Sorting Peptide Assemblies in Living Cells for Simultaneous Organelle-Targeting. Journal of the American Chemical Society, 2022, 144, 24177-24187.
  4. Zhang Z, Liu X, Tian F, Wang S, Hu B, Yu Z*. Aspartate Isomerization Regulates in Situ Assembly of Peptides into Supramolecular Probes for Detection of Protein Carboxyl Methyltransferase in Bladder Cancer. Nano Letters, 2025, 25, 3923-3930.
  5. Chen N#, Zhang Z#, Liu X, Wang H, Guo R-C, Wang H, Hu B, Shi Y*, Zhang P*, Liu Z, Yu Z*. Sulfatase-Induced In Situ Formulation of Antineoplastic Supra-PROTACs. Journal of the American Chemical Society, 2024, 146, 10753-10766.
  6. Yu X#, Wang H#, Liu X, Huang L, Song N, Song Y, Mo X, Lou S, Shi L, Yu Z*. Assembling Synergistic Peptide-Drug Conjugates for Dual-Targeted Treatment of Cancer Metastasis. Nano Today, 2022, 46, 101594.
  7. Li M, Wang Z, Liu X, Song N, Song Y, Shi X, Liu J*, Liu J*, Yu Z*. Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy. Journal of Controlled Release, 2021, 340, 35-47.
  8. Mo X, Song J, Liu X, Guo R-C, Hu B, Yu Z* Redox-Regulated In Situ Seed-Induced Assembly of Peptides. Biomacromolecules, 2024, 25, 2497-2508.
  9. Song J, Mo X, Liu X, Hu B, Zhang Z, Yu Z* Arginine Methylation Regulates Self-Assembly of Peptides. Macromolecular Rapid Communications, 2023, 44, 2300308.
  10. Wang W, Wang H, Zhang Z, Liu X, Hu B, Tian F, Ye Z, Shi L, Yu Z*. In Situ Liquid-Liquid Phase Separation of Peptides Into Droplets Targeting Membraneless Organelles for Enhanced Cancer Chemotherapy. Advanced Materials, 2025, 37, e2420399.
  11. Tian F#, Guo R-C#, Wu C, Liu X, Zhang Z, Wang Y, Wang H, Li G, and Yu Z*. Assembly of Glycopeptides in Living cells Resembling Viral Infection for Cargo Delivery. Angewandte Chemie International Edition, 2024, 63, e202404703.
  12. Song Y, Li M, Song N, Liu X, Wu G, Zhou H, Long J, Yu, Z*. Self-Amplifying Assembly of Peptides in Macrophages for Enhanced Inflammatory Treatment. Journal of the American Chemical Society, 2022, 144, 6907-6917.
  13. Song N, Song Y, Hu B, Liu X, Yu X, Zhou, H, Long, J, Yu Z*. Persistent Endoplasmic Reticulum Stress Stimulated by Peptide Assemblies for Sensitizing Cancer Chemotherapy. Advanced Healthcare Materials, 2022, 11, 2202039.
  14. Song N, Sun Z, Wang Bo, Liu X, Hu B, Zhang S*, Yu Z*. Suicide Gene Delivery by Morphology-Adaptable Enantiomeric Peptide Assemblies for Combined Ovarian Cancer Therapy. Acta Biomaterialia, 2024, 175, 250-261.
  15. Hu B, Song N, Cao Y, Li M, Liu X, Zhou Z, Yu Z*. Noncanonical amino acids for hypoxia-responsive peptide self-assembly and fluorescence. Journal of the American Chemical Society, 2021, 143, 13854-13864.
  16. Wang H#, Song Y#, Wang W, Chen N, Hu B, Liu X, Zhang Z, Yu Z*.Organelle-Mediated Dissipative Self-Assembly of Peptides in Living Cells. Journal of the American Chemical Society, 2024, 146, 330-341.